Two unbeaten Premier League teams currently sitting inside the top four lock horns at the London Stadium on Saturday afternoon as West Ham United play host to reigning champions Manchester City.
Seeking to climb into the top half of the Premier League table, Manchester United play host to Brighton & Hove Albion at Old Trafford on Saturday afternoon.
On the back of a brilliant start to life under Ange Postecoglou, Tottenham Hotspur resume Premier League duties at home to Sheffield United on Saturday afternoon.
Still without a home win in the 2023-24 Premier League season, Fulham seek to right those wrongs when they welcome newly-promoted Luton Town to Craven Cottage on Saturday.
Aston Villa will be looking to leapfrog Crystal Palace in the Premier League table when they welcome the Eagles to Villa Park on Saturday afternoon.
Aiming to pick up where they left off before the international break, Liverpool take on Wolverhampton Wanderers in Saturday's early Premier League kickoff.
Jurgen Klopp's men swatted aside Aston Villa 3-0 in gameweek four, while their hosts were on the receiving end of a 3-2 beating at the hands of Crystal Palace.