FC Samartex will hope to keep firm grip at the top of the table when they host Accra Great Olympics on Saturday.
Aduana FC will host relegation-threatened Karela United at the Nana Agyeman Badu I Park in Dormaa this Saturday, marking their return home after a 1-0 defeat against Bibiani GoldStars FC last weekend.
Champions Medeama SC will welcome giants Asante Kotoko to the Akoon Park in arguably the biggest fixture of Ghana Premier League match-week 28.
Hoping to replicate first rounds astonishing Dun’s Park slaughter, Nations FC will sit at home as Bibiani Gold Stars head south to square off with them in Saturday's Premier League encounter.
Seeking their second Bechem Park triumph of the month at the third attempt, Bechem United welcome Heart of Lions to their Tano South district home for a Saturday lunchtime Premier League contest.
The Royals secured back-to-back victories after recording a late five-goal thriller win over Berekum Chelsea in the Ghana Premier League match-week 28 fixture on Friday afternoon.