The Ghanaian couldn't help his side to snatch the maximum points at the Football stadium MŠK Žilina in the first leg of the first round of the qualifiers.
Agyiri's goal was his fourth in two matches after netting the consolation for Levadia in the 51st minute.
The former Right to Dream Academy trainee scored a hat-trick last Sunday against Nõmme Kalju FC in the Estonian professional topflight league.
Agyiri's Ghana compatriots Samuel Gidi and Henry Addo starred for Žilina in the first and second-half respectively.
Agyiri has now scored 12 goals and provided 7 assists in 21 games across all competitions this campaign.
By: Pascal Nii Gogo Amoah
