Karela United, currently sitting at 15th place with just one win in their last five matches, will face off against Accra Hearts of Oak at Crosby Awuah Memorial Park on Saturday.
Their last meeting at the CAMS Park ended 1-0 against Hearts of Oak with Humin Dafie scoring in the 94th minute for the home side in the 2021/22 season.
Karela United have 26 points and sit 15th with just one win in their last five matches.
While, Hearts of Oak have managed four away wins this season and are yet to lose a game under their acting head coach David Ocloo.
The phobians have won two of their last three matches under David Ocloo and sit in 4th place with 35 points - 5 points adrift of leaders Aduana FC.
Hearts of Oak will heavily rely on Yaw Amankwah Baafi who is now preferred at right back ahead of Samuel Inkoom. The former Ghanaian International is yet to start for the Phobians in their last three matches.
They also have quality in Salifu Ibrahim, Konadu Yiadom, Victor Aidoo and Benjamain York whiles Karela United have former Hearts of Oak captain Fatawu Mohammed, Samuel Atta Kumi, Rashid Mohammed, Brite Andoh and Ebenezer Ocran to rely on.
The game will be broadcast live on StarTimes Adepa channel 247.